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Gelatin Nanospheres Serve as Building Blocks for Tissue Regenerative Gels

Researchers develop a method for creating colloidal gels for tissue repair that are more biocompatible than previous gels

1 min read
Gelatin Nanospheres Serve as Building Blocks for Tissue Regenerative Gels

Nanowerk has a spotlight piece on a joint research project between Radboud University in the Netherlands and Sichuan University in China that has developed a method for producing oppositely charged gelatin nanospheres that enable a bottom-up approach for injectable gels that can aid in tissue repair.

The research, which was initially published in the Wiley journal Advanced Materials, improves on colloidal gels that have been developed in the past that were often cytotoxic because of their high charge density.

"We have used gelatin since both positively and negatively charged gelatin is commercially available without the need to chemically modify these biopolymers" says Huanan Wang, a PhD student in the Department of Biomaterials at Radboud University Nijmegen Medical Center, in the Nanowerk piece.

As the Nanowerk piece points out, one of the key features of this research was that they demonstrated that commercially available biopolymers, like gelatin, can be used in tissue regeneration without any additional chemical modification that could potentially negatively impact its biocompatibility.

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3D-Stacked CMOS Takes Moore’s Law to New Heights

When transistors can’t get any smaller, the only direction is up

10 min read
An image of stacked squares with yellow flat bars through them.
Emily Cooper

Perhaps the most far-reaching technological achievement over the last 50 years has been the steady march toward ever smaller transistors, fitting them more tightly together, and reducing their power consumption. And yet, ever since the two of us started our careers at Intel more than 20 years ago, we’ve been hearing the alarms that the descent into the infinitesimal was about to end. Yet year after year, brilliant new innovations continue to propel the semiconductor industry further.

Along this journey, we engineers had to change the transistor’s architecture as we continued to scale down area and power consumption while boosting performance. The “planar” transistor designs that took us through the last half of the 20th century gave way to 3D fin-shaped devices by the first half of the 2010s. Now, these too have an end date in sight, with a new gate-all-around (GAA) structure rolling into production soon. But we have to look even further ahead because our ability to scale down even this new transistor architecture, which we call RibbonFET, has its limits.

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