Profile: IsoPlexis Analyzes Thousands of Cells to Fight Cancer

Software and microelectronics fabrication techniques let research identify powerful immune cells

3 min read
Photo showing the IsoPlexis chip.
Photo: IsoPlexis

Cancer patients' bodies contain immune cells that, through successful immunotherapy, can deliver proteins to destroy tumors. But it had been difficult in the past to identify which immune cells were the most powerful.

Now, IsoPlexis, a life sciences startup based in Connecticut, has created “microchips" that quickly identify 42 proteins emitted from thousands of individual cells. Software then analyzes the results to determine which cells are the highly potent “Superman" cells that are the most effective in immunotherapy.

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The Ultimate Transistor Timeline

The transistor’s amazing evolution from point contacts to quantum tunnels

1 min read
A chart showing the timeline of when a transistor was invented and when it was commercialized.

Even as the initial sales receipts for the first transistors to hit the market were being tallied up in 1948, the next generation of transistors had already been invented (see “The First Transistor and How it Worked.”) Since then, engineers have reinvented the transistor over and over again, raiding condensed-matter physics for anything that might offer even the possibility of turning a small signal into a larger one.

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