Facebook Loves It When You Talk About Yourself—and so Does Your Brain

Self-disclosure activates a dopamine-based reward system

2 min read

Hello world. Here's something you don't know about me. I'm allergic to bee stings. And that's not all. For all of third grade, I was convinced that I was the reincarnation of Miles Standish. And the best part is, I had a Coca Cola with my breakfast this morning.

Okay. I admit it. That felt good.

The rest of you have other outlets to produce those good feelings. I don't have a Facebook account and I don't really use Twitter—and according to new research in the journal PNAS, that means I'm missing out on a lot of fun. In a study that will come as no surprise to either of these companies, psychologists at Harvard University found that the brain naturally rewards us for thinking and talking about ourselves. When we rehash our weekend jaunts with a friend, or a whole digital network of friends, we activate the same areas of our brain that perk up when we eat something we like or look at someone we find attractive—the mesolimbic dopamine system.

The structures included in this system have long been thought to reward certain behaviors by sluicing the brain with the pleasure-inducing neurotransmitter dopamine. It's the brain's way of patting us on the back and saying, "Go ahead. You look at that sexy person. You take that money. You eat that carrot cake." Until now, researchers acknowledged that humans have a unique instinct to share their own experiences with those around them, but even as they suspected that the brain rewards them for doing so, they lacked evidence.

Researchers observed activity in the brain, using functional magnetic resonance imaging (fMRI), while participants either talked about their own beliefs or surmised about the beliefs of another person. Reward systems in the brain lit up significantly more when the participants talked about themselves.

In another experiment, the researchers looked at whether the payoff from self-disclosure was hefty enough to outweigh the offer of a monetary reward. In this test, the participants got to choose what kind of question they would answer—a question about their own opinions, a question about the opinions of another person, or a factual true or false question. The investigators promised small payments, with the amount varying from question to question. The majority of participants chose to talk about themselves rather than cash in on the experiment.

The study basically confirms that social network companies employ the single most psychologically intuitive business model ever created. Give people a free service that their brains naturally reward them for using, then sell that community as a product to advertisers. Perhaps the only way Facebook could do better for themselves would be to charge us to post. The evidence suggests we'd be willing.

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This CAD Program Can Design New Organisms

Genetic engineers have a powerful new tool to write and edit DNA code

11 min read
A photo showing machinery in a lab

Foundries such as the Edinburgh Genome Foundry assemble fragments of synthetic DNA and send them to labs for testing in cells.

Edinburgh Genome Foundry, University of Edinburgh

In the next decade, medical science may finally advance cures for some of the most complex diseases that plague humanity. Many diseases are caused by mutations in the human genome, which can either be inherited from our parents (such as in cystic fibrosis), or acquired during life, such as most types of cancer. For some of these conditions, medical researchers have identified the exact mutations that lead to disease; but in many more, they're still seeking answers. And without understanding the cause of a problem, it's pretty tough to find a cure.

We believe that a key enabling technology in this quest is a computer-aided design (CAD) program for genome editing, which our organization is launching this week at the Genome Project-write (GP-write) conference.

With this CAD program, medical researchers will be able to quickly design hundreds of different genomes with any combination of mutations and send the genetic code to a company that manufactures strings of DNA. Those fragments of synthesized DNA can then be sent to a foundry for assembly, and finally to a lab where the designed genomes can be tested in cells. Based on how the cells grow, researchers can use the CAD program to iterate with a new batch of redesigned genomes, sharing data for collaborative efforts. Enabling fast redesign of thousands of variants can only be achieved through automation; at that scale, researchers just might identify the combinations of mutations that are causing genetic diseases. This is the first critical R&D step toward finding cures.

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