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Zapping Sleepers' Brains Causes Lucid Dreaming

Stimulating brain regions associated with self-awareness can make dreamers realize they're dreaming

3 min read
Zapping Sleepers' Brains Causes Lucid Dreaming
Illustration: Randi Klett

Lucid dreams offer us the heady chance to shape our own fates in a fantasy world. In these dreams, sleepers realize they're dreaming and can sometimes take over their dreams' plots, allowing them to turn the tables on their enemies, soar into the sky, or embrace that special someone. Now, researchers in Germany have demonstrated that they can trigger lucid dreams by zapping sleeping people's brains with electricity.   

The researchers used a non-invasive neural stimulation method called transcranial alternating current stimulation (tACS) to send low-intensity electricity through the frontal and temporal lobes of 27 sleepers' brains. These portions of the cerebral cortex are associated with higher order cognitive functions, the researchers write, such as self-reflective awareness, abstract thinking, volition, and metacognition (thinking about thinking). Prior studies have shown that these brain regions are dormant during typical REM sleep, when dreams occur, yet are active during lucid dreams.

The tACS stimulation doesn't cause any noise or sensation, so it could be applied to the sleepers without waking them up. The researchers waited until their monitors showed that the subjects were in REM sleep, turned on the current, then woke up the sleepers and asked about the dreams they were having. The test subjects, none of who had experience with lucid dreaming, rated their dreams on factors like insight into the fact that they were dreaming, control of the dream plot, and dissociation, as if they were watching the dream from a third-person perspective.

Not every jolt of electricity produced a lucid dream report. Crucially, the researchers discovered that the effect depended on the frequency of the stimulation. Using the frequency of 40 Hz, researchers found that 77 percent of the reported dreams were rated lucid. At the frequency of 25 Hz, 58 percent of dreams met the criteria, while other frequencies (2, 6, 12, 70, and 100 Hz) produced a much smaller effect or no effect at all. This makes sense, the researchers say, because prior studies that have recorded the activity of the fronto-temporal lobes during lucid dreams have detected neural oscillations (patterns of neural activity) at the gamma frequency band, centered around 40 Hz. It seems stimulation at that frequency mimicked the brain mechanism that can naturally cause lucid dreams. 

But enough with the science, let's hear about those test subjects' dreams. Here are two reports from the paper:

Example of lucid dream report following 40-Hz stimulation: I was dreaming about lemon cake. It looked translucent, but then again, it didn’t. It was a bit like in an animated movie, like The Simpsons. And then I started falling and the scenery changed and I was talking to Matthias Schweighöfer (a German actor) and two foreign exchange students. And I was wondering about the actor and they told me “yes, you met him before,” so then I realized “oops, you are dreaming.” I mean, while I was dreaming! So strange!

Example of a non-lucid dream report (6 Hz): I am driving in my car, for a long time. Then I arrive at this place where I haven’t been before. And there are a lot of people there. I think maybe I know some of them but they are all in a bad mood so I go to a separate room, all by myself.

Neural stimulation is all the rage these days. A DIY community has sprung up around transcranial direct current stimulation (tDCS), a method similar to that used by the German researchers. Brain hackers are experimenting with using tDCS to tweak their cognition in various ways, such as improving memory and speeding up learning. In labs around the world, researchers are also investigating whether tDCS can be used to treat a wide variety of disorders, including depression, ADHD, and chronic pain. The age of brain zapping is upon us!

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This CAD Program Can Design New Organisms

Genetic engineers have a powerful new tool to write and edit DNA code

11 min read
A photo showing machinery in a lab

Foundries such as the Edinburgh Genome Foundry assemble fragments of synthetic DNA and send them to labs for testing in cells.

Edinburgh Genome Foundry, University of Edinburgh

In the next decade, medical science may finally advance cures for some of the most complex diseases that plague humanity. Many diseases are caused by mutations in the human genome, which can either be inherited from our parents (such as in cystic fibrosis), or acquired during life, such as most types of cancer. For some of these conditions, medical researchers have identified the exact mutations that lead to disease; but in many more, they're still seeking answers. And without understanding the cause of a problem, it's pretty tough to find a cure.

We believe that a key enabling technology in this quest is a computer-aided design (CAD) program for genome editing, which our organization is launching this week at the Genome Project-write (GP-write) conference.

With this CAD program, medical researchers will be able to quickly design hundreds of different genomes with any combination of mutations and send the genetic code to a company that manufactures strings of DNA. Those fragments of synthesized DNA can then be sent to a foundry for assembly, and finally to a lab where the designed genomes can be tested in cells. Based on how the cells grow, researchers can use the CAD program to iterate with a new batch of redesigned genomes, sharing data for collaborative efforts. Enabling fast redesign of thousands of variants can only be achieved through automation; at that scale, researchers just might identify the combinations of mutations that are causing genetic diseases. This is the first critical R&D step toward finding cures.

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