Researchers Using Rat-Robot Hybrid to Design Better Brain Machine Interfaces

Meet RatCar, a small vehicle hooked up to a rat's brain. Japanese scientists hope it can lead to better brain-machine interfaces and wheelchairs

3 min read
Researchers Using Rat-Robot Hybrid to Design Better Brain Machine Interfaces

ratcar

A strange creature, half robot, half rat, has been seen scuttling across a laboratory in Japan. It's RatCar, a rat-vehicle experiment that scientists hope could lead to improved mobility for people with disabilities.

Researchers at the University of Tokyo wanted to see whether rats could control a miniature vehicle through the brain signals that move their limbs. They recently presented their project at the IEEE Engineering in Medicine and Biology Societyannual conference in Buenos Aires, Argentina.

"We wanted to develop a brain-machine interface system aiming for future wheelchairs that paralyzed patients can control only with thought," says Osamu Fukayama of the university's Medical Engineering and Life Science Laboratory. "RatCar is a simplified prototype to develop better electrodes, devices, and algorithms for those systems."

Unlike some brain-machine interface, or BMI, devices that rely on noninvasive EEG to detect neural activity, the RatCar works through direct contact with the brain. Other researchers have used this technique in getting rats to control robotic grippers and monkeys to control computer cursors and even advanced robot arms.

ratcar

In the RatCar, tiny neural electrodes [the dark dots on the tip of the device shown on the photo, right] were implanted in the motor cortex of rat brains, and the animals were suspended under a lightweight, motorized "neuro-robotic platform" with wheels. The objective was to make the vehicle collaborate with the rats to achieve the locomotion they desire.

The rats were trained on the car by towing it around an enclosed area with the motors disengaged. A vision system positioned above tracked the rats by following colored markers on their backs and the vehicle. It fed the positions into a "locomotion estimation model" program that correlated the motion of the animals with readings from the electrodes.

Next the rats were suspended more tightly to the car so their limbs touched the floor only slightly. The researchers then switched the system into "neuro-robotic mode," with the neural signals used to help drive the car. Six out of eight rats used in the study adapted well to the car.

"The vehicle moved forward synchronously with a rat when it was placed inside," says Fukayama, but he adds that the degree to which the car was being controlled by the rat itself was unclear.

Since the rat would be forcibly moved along with the car, measuring its real intentions became a challenging problem. Another difficulty was that only a small percentage of the electrodes actually recorded neural activity, and the recorded neurons didn't necessarily correlate with target movements. 

Fukayama and colleagues Takafumi Suzuki and Kunihiko Mabuchi plan to perform more experiments to address the uncertainties. They want to confirm that the rats can drive the car in different directions and also measure the force that the rats are exerting when trying to move under the car. That way, they could track differences in its motion and the rats' apparent intentions.The less force, the better the neural link is working.

Rats have helped bring about many medical breakthroughs, and we'll see whether they'll help make thought-controlled wheelchairs commonplace.

Images: University of Tokyo's Medical Engineering and Life Science Laboratory

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The Conversation (0)

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An illustration of a woman making a salad with robotic arms around her holding vegetables and other salad ingredients.
Dan Page
Blue

By 2050, the global population aged 65 or more will be nearly double what it is today. The number of people over the age of 80 will triple, approaching half a billion. Supporting an aging population is a worldwide concern, but this demographic shift is especially pronounced in Japan, where more than a third of Japanese will be 65 or older by midcentury.

Toyota Research Institute (TRI), which was established by Toyota Motor Corp. in 2015 to explore autonomous cars, robotics, and “human amplification technologies,” has also been focusing a significant portion of its research on ways to help older people maintain their health, happiness, and independence as long as possible. While an important goal in itself, improving self-sufficiency for the elderly also reduces the amount of support they need from society more broadly. And without technological help, sustaining this population in an effective and dignified manner will grow increasingly difficult—first in Japan, but globally soon after.

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