Nanofilm Serves as Artificial Retina

Greater durability, flexibility and efficiency offer advantages over other artificial retina solutions

2 min read
Nanofilm Serves as Artificial Retina
Image: American Chemical Society

Israel-based Nano Retina made some noise a few years back with its development of so-called “nanoelectrodes” that “interface with the eye’s bipolar neurons” and restart neural stimulation, allowing for messages to go to the brain. The nanoelectrodes served as a kind of artificial retina.

Since then it doesn’t appear that Nano Retina has had much more to report on the development of its implantable device, at least from what its website reveals. But it other Israeli researchers do, in a paper published in the journal Nano Letters. The team from Tel Aviv University, the Hebrew University of Jerusalem Centers for Nanoscience and Nanotechnology and Newcastle University combined semiconductor nanorods and carbon nanotubes to create a wireless, light-sensitive, flexible film that could potentially act in the place of a damaged retina.

The researchers used a plasma polymerized acrylic acid midlayer to make covalent bonds with the semiconductor nanorods directly onto neuro-adhesive, three-dimensional carbon nanotube surfaces.

The researchers have tested the device in a chick’s retina that in normal conditions would not have responded to light. These tests demonstrated that the flexible film absorbed light, which then triggered neuronal activity in the chick.

The researchers claim that this film is more durable, flexible and efficient, as well as better able to stimulate neurons, compared to other competitive devices. While there have been a number of approaches to creating artificial retinas to address diseases of the retina, such as macular degeneration, the stumbling block has largely been getting the device to fit inside the eye itself.

This is why solutions such as Nano Retina’s nanoelectrodes have been so attractive. It would seem, based Nano Retina’s reticence since its initial announcement, that the engineering issues are significant even with a nanoscale solution. Whether this latest research can find a way around them remains to be seen.

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A New Treatment for Arthritis: Vagus-Nerve Stimulation

Studies will soon show whether electroceuticals outperform pharmaceuticals

5 min read
A tablet computer, a smartphone, a grey belt with white stripes, a grey disc, and a small silver rectangle with a wire curled beside it.

Galvani’s system includes a nerve stimulator that attaches to the splenic nerve.

Galvani Bioelectronics

Monique Robroek once had such crippling arthritis that, even with the best available medications, she struggled to walk across a room. But thanks to an electronic implant fitted under her skin, she managed to wean herself off all her drugs and live pain-free for nearly a decade—until recently, when a viral illness made her rheumatoid arthritis (RA) flare up again.

This article is part of our special report Top Tech 2023.

Robroek’s long remission is “very impressive” and rare among patients with RA, says her doctor Frieda Koopman, a rheumatologist at Amsterdam UMC, in the Netherlands. Robroek’s experience highlights the immense potential of so-called bioelectronic medicine, also known as electroceuticals, an emerging field of treatment for diseases that have traditionally been managed with pharmaceuticals alone.

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