Custom Cardiology: A Virtual Heart for Every Patient

Personalized computer models will let cardiologists test life-saving interventions

11 min read
Custom Cardiology: A Virtual Heart for Every Patient
Illustration: James Archer; Hands: Getty Images

A poet might say that each human being’s heart is a unique mystery. Those of us working in the brand new field of computational medicine, however, can now model each of those unique hearts with marvelous accuracy and reveal their secrets. In my laboratory at Johns Hopkins University, my team creates computer models to simulate individual patients’ hearts, which can help cardiologists carry out life-saving treatments. Such models may soon transform medicine, ushering in a new kind of personalized health care with radically improved outcomes.

Biomedical engineers have learned how to use numerical models to generate increasingly sophisticated “virtual organs” over the past decade, and rapid developments in cardiac simulation have made the virtual heart the most complete model of all. It’s a complex replica, as it must mimic the heart’s workings at the molecular scale, through the cellular scale, and up to the level of the whole organ, where muscle tissue expands and contracts with every heartbeat. What’s more, the modeling at these different scales must be tightly integrated to accurately render the constant feedback interactions that govern the functions of the heart.

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Engineers Are Working on a Solar Microgrid To Outlast Lunar Nights

Future lunar bases will need power for mining and astronaut survival

4 min read
A rendering of a lunar base. In the foreground are rows of solar panels and behind them are two astronauts standing in front of a glass dome with plants inside.
P. Carril/ESA

The next time humans land on the moon on the moon, they intend to stay awhile. For the Artemis program program, NASA and its collaborators want to build a sustained presence on the moon, which includes setting up a base at which astronauts can live and work.

One of the crucial elements for a functioning lunar base is a power supply. Sandia National Laboratories, a research and development lab that specializes in building microgrids for military bases, is teaming up with NASA to design one that will work on the moon.

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Trilobite-Inspired Camera Boasts Huge Depth of Field

New camera relies on “metalenses” that could be fabricated using a standard CMOS foundry

3 min read
Black and white image showing different white box shapes in rows

Scanning electron microscope image of the titanium oxide nanopillars that make up the metalens. The scale is 500 nanometers (nm).

NIST

Inspired by the eyes of extinct trilobites, researchers have created a miniature camera with a record-setting depth of field—the distance over which a camera can produce sharp images in a single photo. Their new study reveals that with the aid of artificial intelligence, their device can simultaneously image objects as near as 3 centimeters and as far away as 1.7 kilometers.

Five hundred million years ago, the oceans teemed with horseshoe-crab-like trilobites. Among the most successful of all early animals, these armored invertebrates lived on Earth for roughly 270 million years before going extinct.

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Modeling Microfluidic Organ-on-a-Chip Devices

Register for this webinar to enhance your modeling and design processes for microfluidic organ-on-a-chip devices using COMSOL Multiphysics

1 min read
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Comsol

If you want to enhance your modeling and design processes for microfluidic organ-on-a-chip devices, tune into this webinar.

You will learn methods for simulating the performance and behavior of microfluidic organ-on-a-chip devices and microphysiological systems in COMSOL Multiphysics. Additionally, you will see how to couple multiple physical effects in your model, including chemical transport, particle tracing, and fluid–structure interaction. You will also learn how to distill simulation output to find key design parameters and obtain a high-level description of system performance and behavior.

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